교수/연구실 소개

>대학소개 >교수/연구실 소개

전임교수

정 지 훈Ji Hoon Jeong

전공생물약제학, 약물전달시스템개론
사무실No. 530627
031-290-7783
연구실No. 530629
031-290-7764
e-mailjhjeong@skku.edu

이메일jhjeong@skku.edu
홈페이지http://sites.google.com/view/mplatskku
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학력/경력

최근 연구업적

J. E. Lee, M. G. Kim, Y. L. Jang, M. S. Lee, N. W. Kim, Y. Yin, J. H. Lee, S. Y. Lim, J. W. Park, J. Kim, D. S. Lee, S. H. Kim, J. H. Jeong*, “Self-assembled PEGylated albumin nanoparticles (SPAN) as a platform for cancer chemotherapy and imaging” Drug Delivery 25, 1570-1578, 2018.
N. W. Kim, S. Y. Kim, J. E. Lee, Y. Yin, J. H. Lee, S. Y. Lim, E. S. Kim, H. T. T. Duong, H. K. Kim, S. Kim, J. E. Kim, D. S. Lee, J. Kim, M. S. Lee*, Y. T. Lim*, J. H. Jeong* “Enhanced Cancer Vaccination by In Situ Nanomicelle-Generating Dissolving Microneedles” ACS Nano 12, 9702-9713, 2018.
Y. K. Kim, J. E. Lee, B. Ryplida, C. A. Choi, Z. A. I. Mazrad, G. Lee, S. Lee, I. In, J. H. Jeong*, S. Y. Park* “Redox-responsive FRET-based polymer dot with BODIPY for fluorescence imaging-guided chemotherapy of tumor” European J. Pharmaceutics Biopharmaceutic 132, 200-210, 2018.
H. T. T. Duong, Y. Yin, T. Thambi, T. L. Nguyen, V. H. G. Phanac, M. S. Lee, J. E. Lee, J. Kim, J. H. Jeong*, D. S. Lee* “Smart vaccine delivery based on microneedle arrays decorated with ultra-pH-responsive copolymers for cancer immunotherapy” Biomaterials 185, 13-24, 2018.
M. S. Lee, N. W. Kim, J. E. Lee, M. G. Kim, Y. Yin, S. Y. Kim, B. S. Ko, A. Kim, J. H. Lee, S. Y. Lim, D. W. Lim, S. H. Kim, J. W. Park, Y. T. Lim, J. H. Jeong “Targeted cellular delivery of robust enzyme nanoparticles for the treatment of drug-induced hepatotoxicity and liver injury” Acta Biomaterialia 81, 231-241, 2018.
J. E. Lee, K. Lee, J. A. Nam, A. Kim, S. Y. Lee, M. S. Lee, N. W. Kim, Y. Yin, J. W. Park, S. Y. Park, J. H. Jeong “Cellular delivery of siRNA using poly(2-dimethylaminoethyl methacrylate)-functionalized graphene oxide nano-wrap” Macromol. Res. 26, 1115-1122, 2018.
V. H. G. Phan, H. T. T. Duong, T. Thambi, T. L. Nguyen, M. H. Turabee, Y. Yin, S. H. Kim, J. Kim, J. H. Jeong*, D. S. Lee* “Modularly engineered injectable hybrid hydrogels based on protein-polymer network as potent immunologic adjuvant in vivo” Biomaterials 195, 100-110, 2019.
J. E. Lee, Y. Yin, S. Y. Lim, E S. Kim, J. Jung, D. Kim, J. W. Park, M. S. Lee, J. H. Jeong*, “Enhanced Transfection of Human Mesenchymal Stem Cells Using a Hyaluronic Acid/Calcium Phosphate Hybrid Gene Delivery System” Polymers 11,798-810, 2019.
H. T. T. Duong, T. Thambi, Y. Yin, J. E. Lee, Y. K. Seo, J. H. Jeong*, D. S. Lee*, “Smart pH-Responsive Nanocube-Controlled Delivery of DNA Vaccine and Chemotherapeutic Drugs for Chemoimmunotherapy” ACS Applied Materials & Interfaces 11, 13058-13068, 2019.
Y. Yin, M. S. Lee, J. E. Lee, S. Y. Lim, E S. Kim, J. Jeong, D. Kim.a, J. Kim, D. S. Lee, J. H. Jeong*, “Effective systemic siRNA delivery using dual-layer protected long-circulating nanohydrogel containing inorganic core” Biomaterials Science 7, 3297-3306, 2019.

수행과제

자가조립 나노입자 방출형 용해성 마이크로니들 기반 패치형 백신 기술 개발 (한국연구재단)
비강 스프레이용 독시사이클린 나노구조전달체 제작 (한국연구재단)
크림제형에서 안정한 고형지질나노입자를 이용한 SR크림제품의 개량 (산업자원부)

LDH와 MOF를 활용한 기능성 생리활성물질의 피부투과율 증진과 On/Off 방출 제어가 가능한 복합 소재 개발 (산업자원부)

안질환 치료용 약물 전달용 체내 주사형 임플란트 개발 (한국연구재단)
표적형 약물전달체를 이용한 암 동시 진단·치료 플랫폼 원천기술 개발 (한국연구재단)

연구부문

Polymer-based drug delivery systems for biomacromolecules (nucleic acids, proteins, peptides)
Solubilization of poorly water soluble drugs
Microneedles
Artificial exosomes
Cancer immunotherapy
Therapeutic vaccines
Stem cell engineering and regenerative medicine

성균관대학교 약학대학

skku school of pharmacy

교수/연구실 소개

정 지 훈Ji Hoon Jeong

학력

주요경력

최근 연구업적

수행과제

연구부문