2013. 12 - 2017. 08 동국대학교 생체분자화학연구소, 분자표적기술연구센터 센터장
2015. 03 - 현재 식품의약품안전처 약전토론그룹 전문위원
2013. 03 - 2016. 02 동국대학교 화학과 부교수
2004. 03 - 2013. 02 UST 나노바이오공학전공, 교수(겸직)
2003. 10 - 2013. 02 한국생명공학연구원 선임/책임연구원
2000. 09 - 2003. 08 하버드대학교 화학과 박사후연구원
1997. 09 - 1998. 08 The Scripps Research Institute, La Jolla, 방문연구원
1995. 01 - 2000. 06 포항공대, (선임)연구원 (병역특례)
최근 연구업적
Eun-Kyung Lim, Bong Hyun Chung and Sang J. Chung, Recent Advances in pH-Sensitive Polymeric Nanoparticles for Smart Drug Delivery in Cancer Therapy, Curr. Drug Targets 17, (2016) E-pub ahead (10.2174/1389450117666160602202339) (corresponding author).
S. Y. Lee, W. Kim, Y. G. Lee, H. J. Kang, S.-H. Lee, S. Y. Park, J.-K. Min, S.-R. Lee, Sang J. Chung, Identification of sennoside A as a novel inhibitor of the slingshot (SSH) family proteins related to cancer metastasis, Pharm. Res. 119, 422-430 (2017) (corresponding author).
W. Choe, T. A. Durgannavar, S. J. Chung, Fc-binding ligands of immunoglobulin G: An overview of high affinity proteins and peptides, Materials, 9, 994 (2016) (corresponding author).
Amar B. T. Ghisaidoobe, Wan Soo Yun, and Sang J. Chung, Development of Stable Non-Ionic Lipid Nanoparticles, J. Nanosci. Nanotechnol. 16, 11873–11881 (2016) (corresponding author).
H. J. Kang, W. Choe, J. K. Min, Y. M. Lee, B. M. Kim, S. J. Chung, Cyclic peptide ligand with high binding capacity for affinity purification of immunoglobulin G, J. Chromatogr. A. 1466, 105-12 (2016) (corresponding author).
C. Y. Kim, H. J. Kang, S. J. Chung, H. K. Kim, S. Y. Na, H. J. Kim, Mitochondria-Targeting Chromogenic and Fluorescence Turn-On Probe for the Selective Detection of Cysteine by Caged Oxazolidinoindocyanine, Anal. Chem. 88, 7178-82 (2016) (corresponding author).
H. Lee, H. J. Kang, J. H. Kim, E. S. Lee, S. J. Chung, Intrinsic Förster resonance energy transfer imaging technique (iFIT) for detection of native protein in live cells, Bull. Kor. Soc. Chem., 37, 129-135 (2016) (corresponding author).
Amar B.T. Ghisaidoobe and Sang J. Chung, Functionalized Protein Nanocages as a Platform of Targeted Therapy and Immunodetection, Nanomedicine 10, 3579-3595 (2015) (corresponding author).
Y.-L. Cho, J.-K. Min, K. M. Roh, W. K. Kim, B. S. Han, K.-H. Bae, S. C. Lee, S. J. Chung, H. J. Kang, Phosphoprotein phosphatase 1CB (PPP1CB), a novel adipogenic activator, promotes 3T3-L1 adipogenesis, Biochem. Biophys. Res. Commun. 467, 211-217 (2015) (corresponding author).
H. J. Kang, W. Choe, B. M. Kim, S. J. Chung, IgG Fc-Binding Peptide (FcBP)-Tat Conjugate as a Smart Antibody Carrier into Live Cells, Macromol Res., 23, 876-881 (2015) (corresponding author).
D.C. Lee, H.A. Sohn, Z.Y. Park, S. Oh, Y.K. Kang, K.M. Lee, M. Kang, Y.J. Jang, S.J. Yang, Y.K. Hong, H. Noh, J.A. Kim, D.J. Kim, K.H. Bae, D.M. Kim, S.J. Chung, H.S. Yoo, D.Y. Yu , K.C. Park, Y.I. Yeom, A lactate-induced response to hypoxia, Cell 161, 595-609 (2015).
B. Hwang, S.H. Lee, J.S. Kim, J.H. Moon, I.C. Jeung, N.G. Lee, J. Park, H.J. Hong, Y.L.Cho, H.Jung, Y.J. Park, S.J. Lee, H.G. Lee, W.K. Kim, B.S. Han, K.H. Bae, S.J. Chung, Y.G. Kwon, S.C. Lee, S.J. Kim, J.K. Min, Stimulation of angiogenesis and survival of endothelial cells by human monoclonal Tie2 receptor antibody, Biomaterials 51, 119-28 (2015).
H. J. Kang, J. H. Kim, S. J. Chung, Homogeneous detection of caspase-3 using intrinsic fluorescence resonance energy transfer (iFRET), Biosens. Bioelectron. 67, 413-418 (2015) (corresponding author).
A. B. Ghisaidoobe, S. J. Chung, Intrinsic tryptophan fluorescence in the detection and analysis of proteins: a focus on Förster resonance energy transfer techniques. Int. J. Mol. Sci. 15, 22518-38 (2014).
H. K. Shon, Y.-L. Cho, C. S. Lim, J. S. Choi, S. J. Chung, T. G. Lee, ToF-SIMS analysis of diadenosine triphosphate and didadenosine tetraphosphate using bismuth and argon cluster ion beams, Surface and Interface Analysis 46 (S1), 189-192 (2014),.
J. H. Kim, J. Sumranjit, H. J. Kang, S. J. Chung, Discovery of coumarin derivatives as acceptors for intrinsic fluorescence resonance energy transfer (iFRET) of proteins, Mol. Biosystems 10, 30-3 (2014) (corresponding author).
수행과제
항체 FC-부위 선택적 결합 펩타이드를 활용한 항체-약물 복합체의 개발 (한국연구재단)
영장류 유래 세포를 이용한 아밀로이드 베타타 펩타이드 플라크 형성 기전 연구 및 억제제 검색시스템 개발 (한국생명공학연구원)
FcRn 기반 개인 맞춤형 차세대 ADC 항암파이프라인 개발 (한국연구재단)
무표지 검출시스템 개발을 통한 단백질 인산화 조절 전통천연물의 표적 검증 (한국연구재단)
혈관투과성 측정 및 제어를 위한 기능성 바이오나노컴포지트 개발 (한국연구재단)
항체 약물 접합 조절이 가능한 펩타이드 링커 기술을 이용한 신규 항체 약물 접합체 개발 (연구성과실용화진흥원)
