이 소 아So Ah Lee
- 전공조직재생
- 사무실840214호
031-290-7732 - e-mailsoahlee@skku.edu
연구부문
- 유도만능줄기세포, 생체재료, 조직공학 기술을 이용한 3D 질환 모델링
- 3D 바이오 프린팅 기술을 이용한 High-throughput 3D 생체 조직 플랫폼 구축
Paige S†, Galdos F†, Lee S†,Chin E†, Ranjbarvaziri S, Feyen D, Darsha A, Xu S, Ryan J, Beck A,... , Wu SM. Patient-Specific Induced Pluripotent Stem Cells ImplicateIntrinsic Impaired Contractility in Hypoplastic Left Heart Syndrome, Circulation. 2020 († equalcontribution, IF: 23.1).
Lee S, Stanton AE, Tong X, Yang F. Hydrogels with Enhanced Protein Conjugation EfficiencyReveal Stiffness-induced YAP Localization in Stem Cells Depends on Biochemical Cues. Biomaterials. 2019 (IF: 10.3).
Lee S†, Serpooshan V†,Tong X, Venkatraman S, Lee M, Lee J, Chirikian O, Wu JC, Wu SM, Yang F.Contractile Force Generation by 3D hiPSC-derived Cardiac Tissues is Enhanced byRapid Establishment of Cellular Interconnection in Matrix with Muscle-mimickingStiffness. Biomaterials. 2017(† equal contribution, IF: 10.3)
Full Publication list can be found at https://www.ncbi.nlm.nih.gov/myncbi/soah.lee.1/bibliography/public/
Engineered 3D cardiac muscle organoids using human iPSC-derived cardiomyocytes (Stanford)
In vitro disease modeling of hypertrophic cardiomyopathy using gene-edited MYH7 mutant iPSCs (Stanford)
In vitro disease modeling of hypoplastic left heart syndrome using patient-derived iPSCs (Stanford)
Developed a method to massively expand human iPSC-derived cardiomyocytes (Stanford)
Developed a single-cell patterning method for physiologically-relevant maturation of cardiomyocytes (Stanford)
Engineered 3D smooth muscle tissues using anisotropically engineered gelatin hydrogels and primary smooth muscle cells (Stanford)
Studied YAP-mediated mechanosensing mechanism of human ESCs (Stanford)
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